ACSL3 is a novel GABARAPL2 interactor that links ufmylation and lipid droplet biogenesis

J Cell Sci. 2020 Sep 16;133(18):jcs243477. doi: 10.1242/jcs.243477.

Authors: Franziska Eck, Santosh Phuyal, Matthew D Smith, Manuel Kaulich, Simon Wilkinson, Hesso Farhan, Christian Behrends

PMID:32843575


Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity

Nat Metab. 2019 Oct;1(10):1009-1026. doi: 10.1038/s42255-019-0124-x. Epub 2019 Oct 14.

Authors: Susanne Seitz, Yun Kwon, Götz Hartleben, Julia Jülg, Revathi Sekar, Natalie Krahmer, Bahar Najafi, Anne Loft, Sofiya Gancheva, Kerstin Stemmer, Annette Feuchtinger, Martin Hrabe de Angelis, Timo D Müller, Matthias Mann, Matthias Blüher, Michael Roden, Mauricio Berriel Diaz, Christian Behrends, Jerome Gilleron, Stephan Herzig, Anja Zeigerer

PMID:32694843


AMPK is activated during lysosomal damage via a galectin-ubiquitin signal transduction system

Autophagy. 2020 Aug;16(8):1550-1552. doi: 10.1080/15548627.2020.1788890. Epub 2020 Jul 25.

Authors: Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic

PMID:32597364


The GABARAP Co-Secretome Identified by APEX2-GABARAP Proximity Labelling of Extracellular Vesicles

Cells. 2020 Jun 16;9(6):1468. doi: 10.3390/cells9061468.

Authors: Julia L Sanwald, Gereon Poschmann, Kai Stühler, Christian Behrends, Silke Hoffmann, Dieter Willbold

PMID:32560054


NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

Autophagy. 2020 Jun 16:1-19. doi: 10.1080/15548627.2020.1760623. Online ahead of print.

Authors: Cui-Zan Cai, Chuanbin Yang, Xu-Xu Zhuang, Ning-Ning Yuan, Ming-Yue Wu, Jie-Qiong Tan, Ju-Xian Song, King-Ho Cheung, Huanxing Su, Yi-Tao Wang, Bei-Sha Tang, Christian Behrends, Siva Sundara Kumar Durairajan, Zhenyu Yue, Min Li, Jia-Hong Lu

PMID:32543313


When Separation Causes Activation: Biophysical Control of Bulk Autophagy Initiation

Mol Cell. 2020 May 7;78(3):379-381. doi: 10.1016/j.molcel.2020.04.015.

Authors: Debjani Bhattacharya, Christian Behrends

PMID:32386541


AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System

Mol Cell. 2020 Mar 5;77(5):951-969.e9. doi: 10.1016/j.molcel.2019.12.028. Epub 2020 Jan 28.

Authors: Jingyue Jia, Bhawana Bissa, Lukas Brecht, Lee Allers, Seong Won Choi, Yuexi Gu, Mark Zbinden, Mark R Burge, Graham Timmins, Kenneth Hallows, Christian Behrends, Vojo Deretic

PMID:31995728


Molecular Mechanisms of Selective Autophagy

J Mol Biol. 2020 Jan 3;432(1):1-2. doi: 10.1016/j.jmb.2019.11.010. Epub 2019 Dec 4.

Authors: Sascha Martens, Christian Behrends

PMID:31839401


Regulation of lysosome integrity and lysophagy by the ubiquitin-conjugating enzyme UBE2QL1

Autophagy. 2020 Jan;16(1):179-180. doi: 10.1080/15548627.2019.1687217. Epub 2019 Nov 6.

Authors: Bojana Kravic, Christian Behrends, Hemmo Meyer

PMID:31679434


The ubiquitin-conjugating enzyme UBE2QL1 coordinates lysophagy in response to endolysosomal damage

EMBO Rep. 2019 Oct 4;20(10):e48014. doi: 10.15252/embr.201948014. Epub 2019 Aug 21.

Authors: Lisa Koerver, Chrisovalantis Papadopoulos, Bin Liu, Bojana Kravic, Giulia Rota, Lukas Brecht, Tineke Veenendaal, Mira Polajnar, Anika Bluemke, Michael Ehrmann, Judith Klumperman, Marja Jäättelä, Christian Behrends, Hemmo Meyer

PMID:31432621


Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux

Cells. 2019 Aug 14;8(8):894. doi: 10.3390/cells8080894.

Authors: David P Dannheisig, Eileen Beck, Enrico Calzia, Paul Walther, Christian Behrends, Astrid S Pfister

PMID:31416196


RITA modulates cell migration and invasion by affecting focal adhesion dynamics

Mol Oncol. 2019 Oct;13(10):2121-2141. doi: 10.1002/1878-0261.12551. Epub 2019 Aug 6.

Authors: Samira Catharina Hoock, Andreas Ritter, Kerstin Steinhäuser, Susanne Roth, Christian Behrends, Franz Oswald, Christine Solbach, Frank Louwen, Nina-Naomi Kreis, Juping Yuan

PMID:31353815


Increased Immune Activation by Pathologic α-Synuclein in Parkinson's Disease

Ann Neurol. 2019 Oct;86(4):593-606. doi: 10.1002/ana.25557. Epub 2019 Aug 15.

Authors: Veselin Grozdanov, Luc Bousset, Meike Hoffmeister, Corinna Bliederhaeuser, Christoph Meier, Karine Madiona, Laura Pieri, Martin Kiechle, Pamela J McLean, Jan Kassubek, Christian Behrends, Albert C Ludolph, Jochen H Weishaupt, Ronald Melki, Karin M Danzer

PMID:31343083


The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy

Biochim Biophys Acta Mol Cell Res. 2019 Oct;1866(10):1556-1566. doi: 10.1016/j.bbamcr.2019.07.007. Epub 2019 Jul 19.

Authors: Christina Klimek, Ricarda Jahnke, Judith Wördehoff, Barbara Kathage, Daniela Stadel, Christian Behrends, Alexander Hergovich, Jörg Höhfeld

PMID:31326538


Autophagy, Inflammation, and Metabolism (AIM) Center in its second year

Autophagy. 2019 Oct;15(10):1829-1833. doi: 10.1080/15548627.2019.1634444. Epub 2019 Jul 15.

Authors: Vojo Deretic, Eric Prossnitz, Mark Burge, Matthew J Campen, Judy Cannon, Ke Jian Liu, Meilian Liu, Pamela Hall, Larry A Sklar, Lee Allers, Luisa Mariscal, Sally Ann Garcia, John Weaver, Eric H Baehrecke, Christian Behrends, Francesco Cecconi, Patrice Codogno, Guang-Chao Chen, Zvulun Elazar, Eeva-Liisa Eskelinen, Bernard Fourie, Devrim Gozuacik, Wanjin Hong, Eun-Kyeong Jo, Terje Johansen, Gábor Juhász, Adi Kimchi, Nicholas Ktistakis, Guido Kroemer, Noboru Mizushima, Christian Münz, Fulvio Reggiori, David Rubinsztein, Kevin Ryan, Kate Schroder, Han-Min Shen, Anne Simonsen, Sharon A Tooze, Maria Vaccaro, Tamotsu Yoshimori, Li Yu, Hong Zhang, Daniel J Klionsky

PMID:31234750


LTK is an ER-resident receptor tyrosine kinase that regulates secretion

J Cell Biol. 2019 Aug 5;218(8):2470-2480. doi: 10.1083/jcb.201903068. Epub 2019 Jun 21.

Authors: Federica G Centonze, Veronika Reiterer, Karsten Nalbach, Kota Saito, Krzysztof Pawlowski, Christian Behrends, Hesso Farhan

PMID:31227593


Glia-specific autophagy dysfunction in ALS

Semin Cell Dev Biol. 2020 Mar;99:172-182. doi: 10.1016/j.semcdb.2019.05.024. Epub 2019 May 28.

Authors: Laura Strohm, Christian Behrends

PMID:31132469


Regulation of death receptor signaling by the autophagy protein TP53INP2

EMBO J. 2019 May 15;38(10):e99300. doi: 10.15252/embj.201899300. Epub 2019 Apr 12.

Authors: Saška Ivanova, Mira Polajnar, Alvaro Jesus Narbona-Perez, Maria Isabel Hernandez-Alvarez, Petra Frager, Konstantin Slobodnyuk, Natalia Plana, Angel R Nebreda, Manuel Palacin, Roger R Gomis, Christian Behrends, Antonio Zorzano

PMID:30979779


Lysosomal targeting of the ABC transporter TAPL is determined by membrane-localized charged residues

J Biol Chem. 2019 May 3;294(18):7308-7323. doi: 10.1074/jbc.RA118.007071. Epub 2019 Mar 15.

Authors: Philipp Graab, Christoph Bock, Konstantin Weiss, Alexander Hirth, Nicole Koller, Markus Braner, Jennifer Jung, Frank Loehr, Robert Tampé, Christian Behrends, Rupert Abele

PMID:30877195


Multiple molecular pathways stimulating macroautophagy protect from alpha-synuclein-induced toxicity in human neurons

Neuropharmacology. 2019 May 1;149:13-26. doi: 10.1016/j.neuropharm.2019.01.023. Epub 2019 Feb 4.

Authors: Matthias Höllerhage, Natascha Fussi, Thomas W Rösler, Wolfgang Wurst, Christian Behrends, Günter U Höglinger

PMID:30731136


Loss of the selective autophagy receptor p62 impairs murine myeloid leukemia progression and mitophagy

Blood. 2019 Jan 10;133(2):168-179. doi: 10.1182/blood-2018-02-833475. Epub 2018 Nov 29.

Authors: The Duy Nguyen, Shabnam Shaid, Olesya Vakhrusheva, Sebastian E Koschade, Kevin Klann, Marlyn Thölken, Fatima Baker, Jing Zhang, Thomas Oellerich, Duran Sürün, Anja Derlet, Isabella Haberbosch, Stefan Eimer, Heinz D Osiewacz, Christian Behrends, Christian Münch, Ivan Dikic, Christian H Brandts

PMID:30498063


Exosomal secretion of α-synuclein as protective mechanism after upstream blockage of macroautophagy

Cell Death Dis. 2018 Jul 9;9(7):757. doi: 10.1038/s41419-018-0816-2.

Authors: Natascha Fussi, Matthias Höllerhage, Tasnim Chakroun, Niko-Petteri Nykänen, Thomas W Rösler, Thomas Koeglsperger, Wolfgang Wurst, Christian Behrends, Günter U Höglinger

PMID:29988147


Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80

J Immunol. 2018 Aug 15;201(4):1275-1286. doi: 10.4049/jimmunol.1800059. Epub 2018 Jul 6.

Authors: Sebastian Neuss, Yvonne Bartel, Christina Born, Sandra Weil, Joachim Koch, Christian Behrends, Meike Hoffmeister, Alexander Steinle

PMID:29980609


Autophagy, Inflammation, and Metabolism (AIM) Center of Biomedical Research Excellence: supporting the next generation of autophagy researchers and fostering international collaborations

Autophagy. 2018;14(6):925-929. doi: 10.1080/15548627.2018.1465784.

Authors: Vojo Deretic, Eric Prossnitz, Mark Burge, Matthew J Campen, Judy Cannon, Ke Jian Liu, Larry A Sklar, Lee Allers, Sally Ann Garcia, Eric H Baehrecke, Christian Behrends, Francesco Cecconi, Patrice Codogno, Guang-Chao Chen, Zvulun Elazar, Eeva-Liisa Eskelinen, Bernard Fourie, Devrim Gozuacik, Wanjin Hong, Gokhan Hotamisligi, Marja Jäättelä, Eun-Kyeong Jo, Terje Johansen, Gábor Juhász, Adi Kimchi, Nicholas Ktistakis, Guido Kroemer, Noboru MIzushima, Christian Münz, Fulvio Reggiori, David Rubinsztein, Kevin Ryan, Kate Schroder, Anne Simonsen, Sharon Tooze, Maria I Vaccaro, Tamotsu Yoshimori, Li Yu, Hong Zhang, Daniel J Klionsky

PMID:29938597


AT 101 induces early mitochondrial dysfunction and HMOX1 (heme oxygenase 1) to trigger mitophagic cell death in glioma cells

Autophagy. 2018;14(10):1693-1709. doi: 10.1080/15548627.2018.1476812. Epub 2018 Jul 21.

Authors: Nina Meyer, Svenja Zielke, Jonas B Michaelis, Benedikt Linder, Verena Warnsmann, Stefanie Rakel, Heinz D Osiewacz, Simone Fulda, Michel Mittelbronn, Christian Münch, Christian Behrends, Donat Kögel

PMID:29938581


Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors

Stem Cell Reports. 2018 Apr 10;10(4):1184-1192. doi: 10.1016/j.stemcr.2018.03.010.

Authors: Jasmine Kolb, Marie Anders-Maurer, Tanja Müller, Ann-Christin Hau, Britta Moyo Grebbin, Wiebke Kallenborn-Gerhardt, Christian Behrends, Dorothea Schulte

PMID:29641989


The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCF<sup>FBXW</sup><sup>7</sup> function

EMBO J. 2018 Mar 15;37(6):e99170. doi: 10.15252/embj.201899170.

Authors: Veronika Reiterer, Cristina Figueras-Puig, Francois Le Guerroue, Stefano Confalonieri, Manuela Vecchi, Dasaradha Jalapothu, Sandip M Kanse, Raymond J Deshaies, Pier Paolo Di Fiore, Christian Behrends, Hesso Farhan

PMID:29545456


Oocyte DNA damage quality control requires consecutive interplay of CHK2 and CK1 to activate p63

Nat Struct Mol Biol. 2018 Mar;25(3):261-269. doi: 10.1038/s41594-018-0035-7. Epub 2018 Feb 26.

Authors: Marcel Tuppi, Sebastian Kehrloesser, Daniel W Coutandin, Valerio Rossi, Laura M Luh, Alexander Strubel, Katharina Hötte, Meike Hoffmeister, Birgit Schäfer, Tiago De Oliveira, Florian Greten, Ernst H K Stelzer, Stefan Knapp, Massimo De Felici, Christian Behrends, Francesca Gioia Klinger, Volker Dötsch

PMID:29483652


CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis

Dev Cell. 2018 Jan 22;44(2):217-232.e11. doi: 10.1016/j.devcel.2017.11.024. Epub 2017 Dec 28.

Authors: Matthew D Smith, Margaret E Harley, Alain J Kemp, Jimi Wills, Martin Lee, Mark Arends, Alex von Kriegsheim, Christian Behrends, Simon Wilkinson

PMID:29290589


Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway

Mol Cell. 2017 Nov 16;68(4):786-796.e6. doi: 10.1016/j.molcel.2017.10.029.

Authors: François Le Guerroué, Franziska Eck, Jennifer Jung, Tatjana Starzetz, Michel Mittelbronn, Manuel Kaulich, Christian Behrends

PMID:29149599


Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins

Nat Commun. 2017 Nov 16;8(1):1537. doi: 10.1038/s41467-017-00859-z.

Authors: Alice C Newman, Alain J Kemp, Yvette Drabsch, Christian Behrends, Simon Wilkinson

PMID:29146913


Effects of soluble CPE on glioma cell migration are associated with mTOR activation and enhanced glucose flux

Oncotarget. 2017 Jun 27;8(40):67567-67591. doi: 10.18632/oncotarget.18747. eCollection 2017 Sep 15.

Authors: Elena I Ilina, Angela Armento, Leticia Garea Sanchez, Marina Reichlmeir, Yannick Braun, Cornelia Penski, David Capper, Felix Sahm, Lukas Jennewein, Patrick N Harter, Sven Zukunft, Ingrid Fleming, Dorothea Schulte, Francois Le Guerroué, Christian Behrends, Michael W Ronellenfitsch, Ulrike Naumann, Michel Mittelbronn

PMID:28978054


Protocol for Establishing a Multiplex Image-based Autophagy RNAi Screen in Cell Cultures

Bio Protoc. 2017 Sep 5;7(17):27982478. doi: 10.21769/BioProtoc.2540.

Authors: Jennifer Jung, Christian Behrends

PMID:28966949


Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation

Cell Rep. 2017 Aug 29;20(9):2277. doi: 10.1016/j.celrep.2017.08.054.

Authors: Angelica Aguilera-Gomez, Margarita Zacharogianni, Marinke M van Oorschot, Heide Genau, Rianne Grond, Tineke Veenendaal, Kristina S Sinsimer, Elisabeth A Gavis, Christian Behrends, Catherine Rabouille

PMID:28854374


Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation

J Biol Chem. 2017 Sep 15;292(37):15340-15351. doi: 10.1074/jbc.M117.794255. Epub 2017 Aug 7.

Authors: Svenja Wiechmann, Anne Gärtner, Andreas Kniss, Andreas Stengl, Christian Behrends, Vladimir V Rogov, Manuel S Rodriguez, Volker Dötsch, Stefan Müller, Andreas Ernst

PMID:28784659


Expanding the host cell ubiquitylation machinery targeting cytosolic <em>Salmonella</em>

EMBO Rep. 2017 Sep;18(9):1572-1585. doi: 10.15252/embr.201643851. Epub 2017 Aug 6.

Authors: Mira Polajnar, Marina S Dietz, Mike Heilemann, Christian Behrends

PMID:28784601


Phospho-Rasputin Stabilization by Sec16 Is Required for Stress Granule Formation upon Amino Acid Starvation

Cell Rep. 2017 Jul 25;20(4):935-948. doi: 10.1016/j.celrep.2017.06.042.

Authors: Angelica Aguilera-Gomez, Margarita Zacharogianni, Marinke M van Oorschot, Heide Genau, Rianne Grond, Tineke Veenendaal, Kristina S Sinsimer, Elizabeth R Gavis, Christian Behrends, Catherine Rabouille

PMID:28746877


Multifaceted role of SMCR8 as autophagy regulator

Small GTPases. 2020 Jan;11(1):53-61. doi: 10.1080/21541248.2017.1346553. Epub 2017 Oct 3.

Authors: Jennifer Jung, Christian Behrends

PMID:28696821


Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator

Elife. 2017 Feb 14;6:e23063. doi: 10.7554/eLife.23063.

Authors: Jennifer Jung, Arnab Nayak, Véronique Schaeffer, Tatjana Starzetz, Achim K Kirsch, Stefan Müller, Ivan Dikic, Michel Mittelbronn, Christian Behrends

PMID:28195531


The pseudophosphatase STYX targets the F-box of FBXW7 and inhibits SCFFBXW7 function

EMBO J. 2017 Feb 1;36(3):260-273. doi: 10.15252/embj.201694795. Epub 2016 Dec 22.

Authors: Veronika Reiterer, Cristina Figueras-Puig, Francois Le Guerroue, Stefano Confalonieri, Manuela Vecchi, Dasaradha Jalapothu, Sandip M Kanse, Raymond J Deshaies, Pier Paolo Di Fiore, Christian Behrends, Hesso Farhan

PMID:28007894


Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice: Role of autophagy

Neurobiol Dis. 2016 Dec;96:294-311. doi: 10.1016/j.nbd.2016.09.010. Epub 2016 Sep 11.

Authors: Christine Altmann, Stefanie Hardt, Caroline Fischer, Juliana Heidler, Hee-Young Lim, Annett Häussler, Boris Albuquerque, Béla Zimmer, Christine Möser, Christian Behrends, Frank Koentgen, Ilka Wittig, Mirko H H Schmidt, Albrecht M Clement, Thomas Deller, Irmgard Tegeder

PMID:27629805


An siRNA screen for ATG protein depletion reveals the extent of the unconventional functions of the autophagy proteome in virus replication

J Cell Biol. 2016 Aug 29;214(5):619-35. doi: 10.1083/jcb.201602046.

Authors: Mario Mauthe, Martijn Langereis, Jennifer Jung, Xingdong Zhou, Alex Jones, Wienand Omta, Sharon A Tooze, Björn Stork, Søren Riis Paludan, Tero Ahola, Dave Egan, Christian Behrends, Michal Mokry, Cornelis de Haan, Frank van Kuppeveld, Fulvio Reggiori

PMID:27573464


Unveiling ubiquitinome rearrangements induced by Salmonella infection

Autophagy. 2016 Sep;12(9):1683-4. doi: 10.1080/15548627.2016.1203490. Epub 2016 Jul 28.

Authors: Tihana Bionda, Christian Behrends

PMID:27467224


GABARAP proteins as scaffolds in localized TIAM1-RAC1 signaling

Mol Cell Oncol. 2015 Apr 14;3(1):e1027440. doi: 10.1080/23723556.2015.1027440. eCollection 2016 Jan.

Authors: Heide Marika Genau, Christian Behrends

PMID:27308540


Global Analysis of Host and Bacterial Ubiquitinome in Response to Salmonella Typhimurium Infection

Mol Cell. 2016 Jun 16;62(6):967-981. doi: 10.1016/j.molcel.2016.04.015. Epub 2016 May 19.

Authors: Evgenij Fiskin, Tihana Bionda, Ivan Dikic, Christian Behrends

PMID:27211868


Diagnostic and clinical relevance of the autophago-lysosomal network in human gliomas

Oncotarget. 2016 Apr 12;7(15):20016-32. doi: 10.18632/oncotarget.7910.

Authors: Lukas Jennewein, Michael W Ronellenfitsch, Patrick Antonietti, Elena I Ilina, Jennifer Jung, Daniela Stadel, Lisa-Marie Flohr, Jenny Zinke, Janusz von Renesse, Ulrich Drott, Peter Baumgarten, Anne K Braczynski, Cornelia Penski, Michael C Burger, Jean-Philippe Theurillat, Joachim P Steinbach, Karl-Heinz Plate, Ivan Dikic, Simone Fulda, Christian Brandts, Donat Kögel, Christian Behrends, Patrick N Harter, Michel Mittelbronn

PMID:26956048


TBC1D14 regulates autophagy via the TRAPP complex and ATG9 traffic

EMBO J. 2016 Feb 1;35(3):281-301. doi: 10.15252/embj.201592695. Epub 2015 Dec 28.

Authors: Christopher A Lamb, Stefanie Nühlen, Delphine Judith, David Frith, Ambrosius P Snijders, Christian Behrends, Sharon A Tooze

PMID:26711178


TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export

Mol Cell. 2015 Oct 1;60(1):89-104. doi: 10.1016/j.molcel.2015.09.010.

Authors: Daniela Stadel, Valentina Millarte, Kerstin D Tillmann, Jessica Huber, Bat-Chen Tamin-Yecheskel, Masato Akutsu, Alik Demishtein, Bruria Ben-Zeev, Yair Anikster, Franck Perez, Volker Dötsch, Zvulun Elazar, Vladimir Rogov, Hesso Farhan, Christian Behrends

PMID:26431026


Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9

Mol Cell Biol. 2015 Jul;35(14):2479-94. doi: 10.1128/MCB.00125-15. Epub 2015 May 11.

Authors: Jennifer Jung, Heide Marika Genau, Christian Behrends

PMID:25963655


CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling

Mol Cell. 2015 Mar 19;57(6):995-1010. doi: 10.1016/j.molcel.2014.12.040. Epub 2015 Feb 12.

Authors: Heide Marika Genau, Jessica Huber, Francesco Baschieri, Masato Akutsu, Volker Dötsch, Hesso Farhan, Vladimir Rogov, Christian Behrends

PMID:25684205